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How to Use THC and CBD Together

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January 24, 2023

You hear a lot of confusing cannabis acronyms, and probably wonder: what the heck do they all mean and why do there need to be so many? THC is one you probably know, and CBD too. THC and CBD are both phytocannabinoids, and they are found in the cannabis plant. There are over 100 known cannabinoids, with researchers believing there are more that have been yet to be discovered. THC and CBD are among the most popular, and you’ll probably hear them being talked about the most. 

You might know THC as the cannabinoid responsible for getting you high, and you’d be correct! THC works by binding to the CB1 receptors found in the endocannabinoid system. The endocannabinoid system is a bodily system every human being has, and even every animal! 

The endocannabinoid system

It might sound like pseudoscience, but trust us, the endocannabinoid system is very well-documented. UCLA, for example, has an entire initiative dedicated to cannabinoid research. The endocannabinoid system was discovered decades ago, and researchers believe its primary purpose is to help regulate the body and bring it to a place of homeostasis. CBD also interacts with the body’s endocannabinoid system, but in a more roundabout way. Instead of binding directly to either receptor, CBD works mainly by regulating inflammation in the body. 

Mixing CBD and THC

Let’s talk about mixing CBD and THC. Many people wonder if this is okay, or something people do. Think about it like this: THC and CBD already co-exist together in the cannabis plant, and in literally every joint/bowl/etc you’ve ever smoked! If you’ve consumed a high-THC cannabis product, smoking or not, you’ve mixed CBD and THC. Cannabis is naturally riddled with cannabinoids, both THC and CBD. So when you consume cannabis, you’re already mixing CBD and THC! 

So to simplify the answer, yes. Mixing CBD and THC products is perfectly fine, great even, because of something known as the entourage effect. The entourage effect is the idea that cannabinoids work better together, instead of apart. Since hemp-derived CBD joined the legal marketplace, we hear a lot about something called full-spectrum CBD. Full-spectrum CBD is simply a hemp-derived CBD product with a full cannabinoid and terpene profile. It’s the idea of using the entire plant, instead of just isolating bits and pieces of it. 

Full-spectrum profiles have both THC and CBD

In a full-spectrum profile, you should be able to find potent concentrations of CBD, CBN, and CBC. There should be THC present too, but the amount depends on whether or not the product is hemp-derived or derived from high-THC cannabis. You’ll also find CBD isolate extracts, which basically means the product is CBD alone, without THC or other plant compounds present. 

A little about terpenes

Terpenes will also be found in a full-spectrum profile, and terpenes are responsible for the way cannabis smells and tastes. The most popular terpenes include:

  • Linalool
  • Limonene
  • B-caryophyllene
  • Myrcene

Terpenes are thought to have some pretty powerful benefits of their own, like anti-inflammatory and antiseptic properties. You won’t find any additional cannabinoids or terpenes, and there are many experts who think CBD isolate should be removed completely. We believe some cannabinoids are better than none, but we also support the idea behind the entourage effect. What could be better than the whole plant?

The entourage effect

Let’s talk a little more about the entourage effect. When you consume cannabinoids together, your body will better utilize them. The cannabinoids interact in such a way that creates balance in your body. Most of the entourage effect research we have available is exploring the use of THC and CBD specifically. 

Dr. Ethan Russo is one of the biggest supporters of the entourage effect, and he even wrote an insightful review making a case for the phenomenon. This review highlighted different pieces of evidence to support the entourage effect (sometimes called cannabis synergy), and mentioned how CBD and CBG were shown to be effective against fighting MRSA, a bacterial skin infection. Mixing your CBD and THC might give you more powerful results than you could have thought possible, though we don’t have conclusive evidence. 

CBD can negate some of THC’s effects

Have you ever had too much THC? If you have, you know it isn’t an enjoyable experience. Your heart might race, you’ll probably feel anxious and paranoid. An unexpected benefit of the entourage effect is CBD’s ability to cancel THC. If you have too much THC, take some CBD and wait a few minutes. You should start to feel the high come down! This is a great trick for new consumers, and even seasoned consumers who have had a little too much. This is the entourage effect at work, too, just in a different way! 

Save time, track your consumption

This is why tracking your consumption is important. The Farmer’s Wife is launching a patient journal that allows medical marijuana consumers to keep track of how much medicine they’re currently taking. You can write about your emotional and physical state, as well as exactly which product you consumed and how much. This way, you always have a written reference as to how much you need. Dosing your medicine can be challenging, especially if you notice it frequently fluctuates. Keeping track of how you feel can be a great way to identify some potential triggers, and do what you can to reduce them. For example, you might not respond to a certain product each and every time, but the same product with a little bit higher THC content is your go-to. We can’t possibly be expected to remember how we feel at every turn, which is where journaling comes in handy. 

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